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1

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

Qi, Lei S., Larson, Matthew H., Gilbert, Luke A., Doudna, Jennifer A., Weissman, Jonathan S., Arkin, Adam P., Lim, Wendell A.

Journal:

Year:

2013

Language:

english

File:

PDF, 843 KB

english, 2013

2

Beyond editing: repurposing CRISPR–Cas9 for precision genome regulation and interrogation

Dominguez, Antonia A., Lim, Wendell A., Qi, Lei S.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2015

Language:

english

File:

PDF, 748 KB

english, 2015

3

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

Gilbert, Luke A., Larson, Matthew H., Morsut, Leonardo, Liu, Zairan, Brar, Gloria A., Torres, Sandra E., Stern-Ginossar, Noam, Brandman, Onn, Whitehead, Evan H., Doudna, Jennifer A., Lim, Wendell A.,

Journal:

Year:

2013

Language:

english

File:

PDF, 689 KB

english, 2013

4

Domains, Motifs, and Scaffolds: The Role of Modular Interactions in the Evolution and Wiring of Cell Signaling Circuits

Bhattacharyya, Roby P., Reményi, Attila, Yeh, Brian J., Lim, Wendell A.

Journal:

Annual Review of Biochemistry

Year:

2006

Language:

english

File:

PDF, 2.34 MB

english, 2006

5

CRISPR interference (CRISPRi) for sequence-specific control of gene expression

Larson, Matthew H, Gilbert, Luke A, Wang, Xiaowo, Lim, Wendell A, Weissman, Jonathan S, Qi, Lei S

Journal:

Nature Protocols

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

6

Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds

Zalatan, Jesse G., Lee, Michael E., Almeida, Ricardo, Gilbert, Luke A., Whitehead, Evan H., La Russa, Marie, Tsai, Jordan C., Weissman, Jonathan S., Dueber, John E., Qi, Lei S., Lim, Wendell A.

Journal:

Year:

2015

Language:

english

File:

PDF, 662 KB

english, 2015

7

Engineering Therapeutic T Cells: From Synthetic Biology to Clinical Trials

Esensten, Jonathan H., Bluestone, Jeffrey A., Lim, Wendell A.

Journal:

Annual Review of Pathology Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 935 KB

english, 2017

8

The Principles of Engineering Immune Cells to Treat Cancer

Lim, Wendell A., June, Carl H.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.93 MB

english, 2017

9

Cellular perception and misperception: Internal models for decision-making shaped by evolutionary experience

Mitchell, Amir, Lim, Wendell

Journal:

Year:

2016

Language:

english

File:

PDF, 577 KB

english, 2016

10

Expanding the CRISPR imaging toolset with Staphylococcus aureus Cas9 for simultaneous imaging of multiple genomic loci

Chen, Baohui, Hu, Jeffrey, Almeida, Ricardo, Liu, Harrison, Balakrishnan, Sanjeev, Covill-Cooke, Christian, Lim, Wendell A., Huang, Bo

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 9.02 MB

english, 2016

11

Alternative packing arrangements in the hydrophobic core of λrepresser

Lim, Wendell A., Sauer, Robert T.

Journal:

Year:

1989

File:

PDF, 751 KB

1989

12

Synthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic Capabilities

Roybal, Kole T., Lim, Wendell A.

Journal:

Annual Review of Immunology

Year:

2017

Language:

english

File:

PDF, 846 KB

english, 2017

13

Modular engineering of cellular signaling proteins and networks

Gordley, Russell M, Bugaj, Lukasz J, Lim, Wendell A

Journal:

Current Opinion in Structural Biology

Year:

2016

Language:

english

File:

PDF, 1.07 MB

english, 2016

14

Engineering cell–cell communication networks: programming multicellular behaviors

Toda, Satoshi, Frankel, Nicholas W, Lim, Wendell A

Journal:

Current Opinion in Chemical Biology

Year:

2019

Language:

english

File:

PDF, 2.22 MB

english, 2019

15

Exploitation of Latent Allostery Enables the Evolution of New Modes of MAP Kinase Regulation

Coyle, Scott M., Flores, Jonathan, Lim, Wendell A.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.70 MB

english, 2013

16

An analysis of packing in the protein folding problem

Richards, Frederic M., Lim, Wendell A.

Journal:

Quarterly Reviews of Biophysics

Year:

1993

Language:

english

File:

PDF, 5.42 MB

english, 1993

17

Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors

Morsut, Leonardo, Roybal, Kole T., Xiong, Xin, Gordley, Russell M., Coyle, Scott M., Thomson, Matthew, Lim, Wendell A.

Journal:

Year:

2016

Language:

english

File:

PDF, 3.98 MB

english, 2016

18

Building a Stable Relationship: Ensuring Homeostasis among Cell Types within a Tissue

Frankel, Nicholas W., Lim, Wendell A.

Journal:

Year:

2018

Language:

english

File:

PDF, 413 KB

english, 2018

19

Engineering synthetic signaling proteins with ultrasensitive input/output control

Dueber, John E, Mirsky, Ethan A, Lim, Wendell A

Journal:

Nature Biotechnology

Year:

2007

Language:

english

File:

PDF, 209 KB

english, 2007

20

Defining Network Topologies that Can Achieve Biochemical Adaptation

Wenzhe Ma, Ala Trusina, Hana El-Samad, Wendell A. Lim, Chao Tang

Journal:

Year:

2009

Language:

english

File:

PDF, 1.00 MB

english, 2009

21

Synthetic biology: lessons from the history of synthetic organic chemistry

Yeh, Brian J, Lim, Wendell A

Journal:

Nature Chemical Biology

Year:

2007

Language:

english

File:

PDF, 1.63 MB

english, 2007

22

Rewiring Cells: Synthetic Biology as a Tool to Interrogate the Organizational Principles of Living Systems

Bashor, Caleb J., Horwitz, Andrew A., Peisajovich, Sergio G., Lim, Wendell A.

Journal:

Annual Review of Biophysics

Year:

2010

Language:

english

File:

PDF, 1.09 MB

english, 2010

23

Bridging cross-cultural gaps in scientific exchange through innovative team challenge workshops

Connie M. Lee, Siyuan Gong, Chao Tang, Wendell A. Lim

Journal:

Quantitative Biology

Year:

2013

Language:

english

File:

PDF, 375 KB

english, 2013

24

Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module

Toettcher, Jared E., Weiner, Orion D., Lim, Wendell A.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.14 MB

english, 2013

25

Sending Mixed Messages for Cell Population Control

Youk, Hyun, Lim, Wendell A.

Journal:

Year:

2014

Language:

english

File:

PDF, 618 KB

english, 2014

26

Engineering T Cells to Treat Cancer: The Convergence of Immuno-Oncology and Synthetic Biology

Choe, Joseph H., Williams, Jasper Z., Lim, Wendell A.

Journal:

Annual Review of Cancer Biology

Year:

2020

File:

PDF, 860 KB

2020

27

Frederic M Richards 1925–2009

Journal:

Nature Structural and Molecular Biology

Year:

2009

Language:

english

File:

PDF, 765 KB

english, 2009

28

Docking interactions in protein kinase and phosphatase networks

Attila Reményi, Matthew C Good, Wendell A Lim

Journal:

Current Opinion in Structural Biology

Year:

2006

Language:

english

File:

PDF, 1.04 MB

english, 2006

29

How signaling proteins integrate multiple inputs: a comparison of N-WASP and Cdk2

Kenneth E Prehoda, Wendell A Lim

Journal:

Current Opinion in Cell Biology

Year:

2002

Language:

english

File:

PDF, 1.04 MB

english, 2002

30

Light-based feedback for controlling intracellular signaling dynamics

Toettcher, Jared E, Gong, Delquin, Lim, Wendell A, Weiner, Orion D

Journal:

Year:

2011

Language:

english

File:

PDF, 770 KB

english, 2011

31

Synthetic biology approaches to engineer T cells

Wu, Chia-Yung, Rupp, Levi J, Roybal, Kole T, Lim, Wendell A

Journal:

Current Opinion in Immunology

Year:

2015

Language:

english

File:

PDF, 745 KB

english, 2015

32

SPIE Proceedings [SPIE Applications in Optical Science and Engineering - Boston, MA (Sunday 15 November 1992)] Mobile Robots VII - SAL: a language for developing an agent-based architecture for mobile robots

Lim, Willie Y., Verzulli, Joe, Wolfe, William J., Chun, Wendell H.

Year:

1993

Language:

english

File:

PDF, 432 KB

english, 1993

33

ChemInform Abstract: VERBRUECKTE POLYCYCLISCHE VERBINDUNGEN 62. MITT. STEREOCHEMIE UND MECHANISMUS DER ELEKTROPHILEN ADDITIONEN AN CYCLOPROPANRINGE

CRISTOL, STANLEY J., LIM, WENDEL Y., DAHL, ALAN R.

Journal:

Chemischer Informationsdienst. Organische Chemie

Year:

1970

File:

PDF, 130 KB

1970

34

Mapping the functional versatility and fragility of Ras GTPase signaling circuits through in vitro network reconstitution

Coyle, Scott M, Lim, Wendell A

Journal:

Year:

2016

Language:

english

File:

PDF, 5.33 MB

english, 2016

35

Build life to understand it

Elowitz, Michael, Lim, Wendell A.

Journal:

Year:

2010

Language:

english

File:

PDF, 308 KB

english, 2010

36

10.1038/77891

Zarrinpar, Ali, Lim, Wendell A.

Journal:

Natural Structural Biology

Year:

2000

Language:

english

File:

PDF, 384 KB

english, 2000

37

Mutational analysis of protein stability

Robert T. Sauer, Wendell A. Lim

Journal:

Current Biology

Year:

1992

Language:

english

File:

PDF, 117 KB

english, 1992

38

SPIE Proceedings [SPIE Photonics for Industrial Applications - Boston, MA (Monday 31 October 1994)] Mobile Robots IX - Small spatial maps for mobile robots

Lim, Willie Y., Wolfe, William J., Chun, Wendell H.

Year:

1995

Language:

english

File:

PDF, 479 KB

english, 1995

39

The Minimal Autoinhibited Unit of the Guanine Nucleotide Exchange Factor Intersectin

Ahmad, K. Farid, Lim, Wendell A., Kobe, Bostjan

Journal:

Year:

2010

Language:

english

File:

PDF, 2.59 MB

english, 2010

40

Alterations of human acellular tissue matrix by gamma irradiation: Histology, biomechanical property, stability, in vitro cell repopulation, and remodeling

Sok-Siam Gouk, Tit-Meng Lim, Swee-Hin Teoh, Wendell Q. Sun

Journal:

Journal of Biomedical Materials Research Part B: Applied Biomaterials

Year:

2008

Language:

english

File:

PDF, 1.12 MB

english, 2008

41

Compactin inhibits insect HMG-CoA reductase and juvenile hormone biosynthesis

Daniel J. Monger, Wendell A. Lim, Ferenc J. Kézdy, John H. Law

Journal:

Biochemical and Biophysical Research Communications

Year:

1982

Language:

english

File:

PDF, 388 KB

english, 1982

42

A Light-Based Feedback Control System for Generating User-Defined Intracelullar Signaling Dynamics

Toettcher, Jared, Gong, Delquin, Lim, Wendell A., Weiner, Orion

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 63 KB

english, 2012

43

Genome Engineering and Disease Research

Xiong, Xin, Chen, Meng, Lim, Wendell A., Zhao, Dehua, Qi, Lei S.

Journal:

Annual Review of Genomics and Human Genetics

Year:

2016

Language:

english

File:

PDF, 962 KB

english, 2016

44

Engineering cytokines and cytokine circuits

Li, Aileen W., Lim, Wendell A.

Journal:

Year:

2020

File:

PDF, 195 KB

2020

45

Structure of the N-WASP EVH1 Domain-WIP Complex: Insight into the Molecular Basis of Wiskott-Aldrich Syndrome

Brian F. Volkman, Kenneth E. Prehoda, Jessica A. Scott, Francis C. Peterson, Wendell A. Lim

Journal:

Year:

2002

Language:

english

File:

PDF, 534 KB

english, 2002

46

An Analysis of the Interactions between the Sem−5 SH3 Domain and Its Ligands Using Molecular Dynamics, Free Energy Calculations, and Sequence Analysis

Wang, Wei, Lim, Wendell A., Jakalian, Araz, Wang, Jian, Wang, Junmei, Luo, Ray, Bayly, Christopher I., Kollman, Peter A.

Journal:

Journal of the American Chemical Society

Year:

2001

Language:

english

File:

PDF, 102 KB

english, 2001

47

Recruitment interactions can override catalytic interactions in determining the functional identity of a protein kinase

Angela P. Won, Joan E. Garbarino and Wendell A. Lim

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.36 MB

english, 2011

48

[ASME ASME 2014 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference - Buffalo, New York, USA (Sunday 17 August 2014)] Volume 2A: 40th Design Automation Conference - Development of a Design Tool for Flow Rate Optimization in the Tata Swach Water Filter

Ricks, Sean T., Lewandowski, John R., Lim, Emmanuel G., Wendell, Dawn M., Winter, Amos G.

Year:

2014

Language:

english

File:

PDF, 2.35 MB

english, 2014

49

[Methods in Enzymology] Protein \3- DNA Interactions Volume 208 || [12] Analysis of DNA-protein interactions by affinity coelectrophoresis

Lim, Wendell A.

Year:

1991

Language:

english

File:

PDF, 1.76 MB

english, 1991

50

Improving SH3 domain ligand selectivity using a non-natural scaffold

Jack T Nguyen, Margaret Porter, Mehran Amoui, W Todd Miller, Ronald N Zuckermann, Wendell A Lim

Journal:

Chemistry & Biology

Year:

2000

Language:

english

File:

PDF, 265 KB

english, 2000

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